Description
Product Characteristics:
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Subcellular location: Secreted
Synonyms: BD 3, BD-3, BD3, beta 103, Beta defensin 103A, Beta defensin 103A precursor, Beta defensin 3, Beta-defensin 103, Beta-defensin 3, D103A_HUMAN, DEF B3, DEFB 103, DEFB 103A, DEFB 3, DEFB-3, DEFB103, DEFB103A, DEFB103B, DEFB3, Defensin, Defensin beta 103A, Defensin beta 3, Defensin like protein, Defensin-like protein, HBD 3, hBD-3, HBD3, HBP 3, HBP3, mBD3.
Target Information: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. [provided by RefSeq, Jul 2008]